What's the Line

NFL Lines for September 28, 2025

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9:30 AM ET
Dublin, Croke Park

Select the favorite:

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1:00 PM ET
Atlanta, GE, Mercedes-Benz Stadium

Select the favorite:

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1:00 PM ET
Buffalo, NY, Highmark Stadium

Select the favorite:

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1:00 PM ET
Detroit, MI, Ford Field

Select the favorite:

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1:00 PM ET
Foxborough, MA, Gillette Stadium

Select the favorite:

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1:00 PM ET
East Rutherford, NJ, MetLife Stadium

Select the favorite:

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1:00 PM ET
Tampa, FL, Raymond James Stadium

Select the favorite:

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1:00 PM ET
Houston, TX, NRG Stadium

Select the favorite:

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4:05 PM ET
Inglewood, CA, SoFi Stadium

Select the favorite:

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4:05 PM ET
Santa Clara, CA, Levi's Stadium

Select the favorite:

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4:25 PM ET
Kansas City, MO, GEHA Field at Arrowhead Stadium

Select the favorite:

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4:25 PM ET
Paradise, NV, Allegiant Stadium

Select the favorite:

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8:20 PM ET
Arlington, TX, AT&T Stadium

Select the favorite:

The games for September 28, 2025 have already started or completed.
@
9:30 AM ET
Dublin, Croke Park
@
1:00 PM ET
Atlanta, GE, Mercedes-Benz Stadium
@
1:00 PM ET
Buffalo, NY, Highmark Stadium
@
1:00 PM ET
Detroit, MI, Ford Field
@
1:00 PM ET
Foxborough, MA, Gillette Stadium
@
1:00 PM ET
East Rutherford, NJ, MetLife Stadium
@
1:00 PM ET
Tampa, FL, Raymond James Stadium
@
1:00 PM ET
Houston, TX, NRG Stadium
@
4:05 PM ET
Inglewood, CA, SoFi Stadium
@
4:05 PM ET
Santa Clara, CA, Levi's Stadium
@
4:25 PM ET
Kansas City, MO, GEHA Field at Arrowhead Stadium
@
4:25 PM ET
Paradise, NV, Allegiant Stadium
@
8:20 PM ET
Arlington, TX, AT&T Stadium
The games for September 28, 2025 have already started or completed.
@
9:30 AM ET
Dublin, Croke Park

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
1:00 PM ET
Atlanta, GE, Mercedes-Benz Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
1:00 PM ET
Buffalo, NY, Highmark Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
1:00 PM ET
Detroit, MI, Ford Field

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
1:00 PM ET
Foxborough, MA, Gillette Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
1:00 PM ET
East Rutherford, NJ, MetLife Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
1:00 PM ET
Tampa, FL, Raymond James Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
1:00 PM ET
Houston, TX, NRG Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
4:05 PM ET
Inglewood, CA, SoFi Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
4:05 PM ET
Santa Clara, CA, Levi's Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
4:25 PM ET
Kansas City, MO, GEHA Field at Arrowhead Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
4:25 PM ET
Paradise, NV, Allegiant Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
8:20 PM ET
Arlington, TX, AT&T Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
The games for September 28, 2025 have already started or completed.
Win Totals - Predict how many games each team will win in the regular season
No win total lines are currently available for NFL.