What's the Line

NFL Lines for September 15, 2025

@
12:20 AM ET
Minneapolis, MN, U.S. Bank Stadium

Select the favorite:

@
11:00 PM ET
Houston, TX, NRG Stadium

Select the favorite:

@
12:20 AM ET
Minneapolis, MN, U.S. Bank Stadium
@
11:00 PM ET
Houston, TX, NRG Stadium
@
12:20 AM ET
Minneapolis, MN, U.S. Bank Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
@
11:00 PM ET
Houston, TX, NRG Stadium

Pick a team and predict their moneyline:

💡 Negative odds = favorite (bet more to win less) | Positive odds = underdog (bet less to win more)
Implied other team: --
Win Totals - Predict how many games each team will win in the regular season

Team Win Totals - September 15, 2025

AFC

AFC East
Team Your Prediction Action
Bills
Dolphins
Patriots
Jets
AFC North
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Ravens
Bengals
Browns
Steelers
AFC South
Team Your Prediction Action
Texans
Colts
Jaguars
Titans
AFC West
Team Your Prediction Action
Broncos
Chiefs
Raiders
Chargers

NFC

NFC East
Team Your Prediction Action
Cowboys
Giants
Eagles
Commanders
NFC North
Team Your Prediction Action
Bears
Lions
Packers
Vikings
NFC South
Team Your Prediction Action
Falcons
Panthers
Saints
Buccaneers
NFC West
Team Your Prediction Action
Cardinals
Rams
49ers
Seahawks